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Phenylbutazone
What is phenylbutazone?
Phenylbutazone (brand names: Butazolidin®, VetriBute®, Butatron®, Phenylbute®) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation in horses only; it is not used in farmed animals.
How is phenylbutazone given?
This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow.
If you miss a dose, give it when you remember. However, if it is close to the time for the next dose, skip the dose you missed, give it at the next scheduled time, and return to the regular dosing schedule. Never give two doses at once or give extra doses.
SERIOUS ADVERSE REACTIONS associated with this drug may occur without warning and could, in rare cases, lead to death. If any of the following signs develop, stop giving phenylbutazone and contact your veterinarian immediately:
This moderate-acting medication should stop working in a few days, although effects can be longer in pets with liver or kidney disease.
Phenylbutazone SHOULD NOT BE USED in pets that:
Phenylbutazone SHOULD BE USED CAUTIOUSLY in:
Certain medications may interact with phenylbutazone, so it is important to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your horse is taking before starting any new treatment. Medications that should be used with caution when given with phenylbutazone include:
Phenylbutazone also interacts with thyroid function tests.
If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Mar 27, 2024.
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